Daily News Analysis

Sigachi Industries Accident

stylish_lining

The pharma unit of Sigachi Industries in Hyderabad, which produces microcrystalline cellulose (MCC), recently experienced a deadly accident.The death toll has risen to 36.

About Microcrystalline Cellulose (MCC)

  • Definition: A free-flowing powder extracted from refined wood pulp (fibrous plant material).

    Chemical Nature: Purified, partially depolymerized cellulose with formula (C6H10O5)n. It is chemically inert, not digested or absorbed in the human body.

    Physical Structure:

    • Made from wood, where cellulose chains are tightly packed and layered, held by cross-linking polymers and hydrogen bonds. It has a crystalline structure due to microfibres with strong 3D internal bonding.

    Properties:

    • Exhibits plastic deformation during compression, increasing interparticle bonding — the key to its excellent binding ability.

    Safety: Natural, fiber-rich, non-toxic, and chewable.

Applications of MCC

  • Widely used in the pharmaceutical industry as a texturizer, extender, emulsifier, and binder.

    Essential for making vitamin supplements and tablets.

    Acts as a bulking agent in food production.

    Helps add weight to drugs and ensures active ingredients work effectively, maintaining drug weight standards.

 

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