Daily News Analysis

Daily News Analysis

Naturally Existing DNA Editing Tool: Bridge Recombinase Mechanism (BRM)

The Bridge Recombinase Mechanism (BRM) is a newly discovered naturally occurring DNA editing tool. It utilizes mobile genetic elements, commonly known as "jumping genes," to perform DNA manipulation. These jumping genes are found in all forms of life and play a crucial role in genetic variation and adaptation. Key Features of BRM: Jumping Genes and Recombinase Enzymes: Jumping

3D Hologram Technology

3D hologram technology creates three-dimensional images that simulate depth and can be viewed from different angles, mimicking real objects. Unlike traditional images that are flat and two-dimensional, holograms appear lifelike and interactive. This is achieved through the manipulation of light waves using principles of interference and diffraction. Principles of 3D Holography: Interferen

Chandipura Virus (CHPV)

Chandipura Virus (CHPV) is a member of the Rhabdoviridae family, which includes the rabies virus. It is known for causing Chandipura encephalitis, a severe neurological condition. The virus was first identified in 1965 in Chandipura village, Maharashtra, during a dengue outbreak. Key Features of Chandipura Virus: Association with Encephalitis: Chandipura Encephalitis: This condition, al

TRANS-FAT

The World Health Organization (WHO) recently published its fifth milestone report on global progress towards eliminating trans fats. This report covers the period from 2018 to 2023. Some key points about this issue: Trans fats are a type of unsaturated fat that has been associated with increased risk of heart disease, stroke and type 2 diabetes. They are often found in processed foods, ba

Streptococcal Toxic Shock Syndrome (STSS)

Streptococcal Toxic Shock Syndrome (STSS) is a severe and potentially life-threatening condition caused by Group A Streptococcus (GAS) bacteria. Here's a detailed overview of STSS based on the information provided: About Streptococcal Toxic Shock Syndrome (STSS) Cause: STSS results from the rapid growth and release of toxins by GAS bacteria. While GAS is more commonly associated with

Nidoviruses

In a variety of vertebrates, researchers had identified 40 novel Nidoviruses using artificial intelligence. About Nidoviruses (notable for their large genomes and complex replication mechanisms) • They are a large and diverse order of positive-strand RNA viruses (largest RNA genomes among viruses) that infect a wide range of vertebrates and invertebrates, including humans, birds, reptil

Reverse Transcriptase (RT) Enzyme

Reverse Transcriptase played a pivotal role in both diagnostic testing and scientific research related to the SARS- CoV-2 virus. About Reverse Transcriptase Enzyme • It Plays a crucial role in the replication of some viruses, including HIV. • It allows the virus to convert its genetic material, which is single-stranded RNA, into double-stranded DNA. This DNA can then integrat

OUTER SPACE GOVERNANCE

Armenia has become the 43rd signatory to NASA's Artemis Accords for lunar exploration. About the Artemis Accords • NASA established the organisation in 2020 in collaboration with the US Department of State and seven founding member nations (Australia, Canada, Italy, Japan, Luxembourg, UAE, and UK). Based on the 1967 Outer Space Treaty and related agreements, such as the Registration Co

NEGLECTED TROPICAL DISEASES (NTDS)

The World Health Organization's recent report, "Global Report on Neglected Tropical Diseases 2024," has brought renewed attention to neglected tropical diseases (NTDs) About Report 1.Reduction in the Need for Interventions: The goal is to reduce the percentage of people requiring interventions against NTDs by 90% by 2030. In 2022, 1.62 billion people needed such

Lignosat

LignoSat is a tiny cuboid satellite measuring 10 cm on each side, made from magnolia wood. It was developed through a collaboration between researchers from Kyoto University and Sumitomo Forestry in Japan. The main goals of LignoSat are to promote the eco-friendliness and cost-effectiveness of using wood for satellite construction. LignoSat is designed to completely burn up u

Hydroxyurea

The Indian Council of Medical Research (ICMR) invited Expressions of Interest (EoI) from various organisations for the “joint development and commercialisation” of low dose or paediatric oral formulation of hydroxyurea to treat sickle cell disease in India. About Hydroxyurea (taken orally in the form of capsules or tablets) • It's a medication used to treat certain types

Daksha Project

Leading Institutions: IIT Bombay Physical Research Laboratory (PRL) Tata Institute of Fundamental Research (TIFR) Raman Research Institute (RRI) Project Goals: The Daksha project aims to advance our understanding of high-energy astrophysical phenomena through the deployment of two high-energy space telescopes. These telescopes will be equipped with advanced sensors capable of dete

What is a Very Short-Range Air Defence System (VSHORADS)

Overview: The Defence Research and Development Organisation (DRDO) successfully conducted two flight tests of the Very Short-Range Air Defence System (VSHORADS) missile. About Very Short-Range Air Defence System (VSHORADS) VSHORADS is a fourth-generation Man Portable Air Defence System (MANPAD) specially designed to counter low-altitude aerial threats over short distances. These ar

Hemophilia A

Overview: Recently, the Union Science and Technology Minister told that India has conducted the first human clinical trial of gene therapy for ‘haemophilia A’ at Christian Medical College – Vellore. About Hemophilia A It is a genetic disorder that affects the body’s ability to form blood clots. It is a rare disorder in which the blood doesn't clot in the typ

What is Gene therapy

It is a technique that modifies a person’s genes to treat or cure disease. Gene therapies can work by several mechanisms: Replacing a disease-causing gene with a healthy copy of the gene   Inactivating a disease-causing gene that is not functioning properly Introducing a new or modified gene into the body to help treat a disease Gene therapy products are being studied to

Milli-second burst detected by AstroSat

Context: AstroSat, India’s first multi-wavelength space-based observatory, has detected bright sub-second X-ray bursts from a new and unique neutron star with ultrahigh magnetic field (magnetar), which can help understand the intriguing extreme astrophysical conditions of magnetars. Magnetars They are neutron stars having an ultrahigh magnetic field that are much stronger

Voice clone-AI

Voice clone fraud has been on the rise in India. AI voice cloning – It is the process of creating a synthetic replica of a person’s voice through machine learning and speech synthesis technology.It is called as voice deepfakesor audio deepfakes. Objective – To achieve a high level of naturalness that sounds exactly like a person&r

AI-powered misinformation biggest short-term threat to global economy

Context: False and misleading information supercharged with cutting-edge artificial intelligence that threatens to erode democracy and polarise society is the top immediate risk to the global economy, the World Economic Forum said in a report on Wednesday. About the report: The World Economic Forum (WEF) report identifies misinformation and disinformation  as the most severe risk ove

Peregrine Lunar Lander

The Peregrine Lunar Lander, also known as Peregrine Mission One, is a lunar lander built by Astrobotic Technology, U.S. It was launched recently carrying payloads for NASA's Commercial Lunar Payload Services program.

Ingenuity helicopter on Mars- USA

NASA has re-established contact with its Ingenuity helicopter on Mars, the US space agency said recently. Ingenuity Mars Helicopter It is a small, autonomous aircraft. that flew to Mars aboard NASA’s Perseverance rover. It was sent to Mars to perform experimental flight tests to determine if powered, controlled flight at the Red Planet was possible. Ingenuity&rsqu

Hepatitis A vaccine ‘Havisure’ 

Recently, the Indian Immunologicals Ltd (IIL) a wholly owned subsidiary of National Dairy Development Board (NDDB) launched India’s first indigenously developed Hepatitis A vaccine ‘Havisure’ in Hyderabad. About Havisure vaccine It is a two-dose vaccine — first dose administered at above 12 months of age and the second at least six months after the first

Are antibiotics over-prescribed in India?

Context: The National Centre for Disease Control (NCDC) recently found that over half of the nearly 10,000 hospital patients surveyed for a study were given antibiotics to prevent, rather than treat, infection.  The survey mapped patients treated on one to five days each at 20 tertiary care institutes across 15 States and two Union Territories between November 2021 and April 2022. It

The blood management system needs a fresh infusion

Context: The COVID-19 pandemic highlighted global health inequalities, prompting policymakers worldwide to advocate for enhanced global health infrastructure as a means to drive economic growth and ensure planetary well-being. However, amid these critical efforts, prioritizing access to blood and its products is deemed essential for establishing a robust global health architecture. The issue of

W1935

W1935 is a brown dwarf star that is 47 light-years away from Earth. It is the 1st auroral candidate outside of the solar system that has been identified through methane emission signatures. It is also the coldest auroral candidate outside of our solar system, with a temperature of about 400 degrees Fahrenheit (200 degrees Celsius). Astronomers using NASA&#

Vondy

It is an all-in-one AI platform that can create content as well as enhance productivity. The application has been developed by New York-based software engineer Rohit Das and New Jersey-based software engineer David Laub. Vondy is free and there are no message limits unlike ChatGPTand also has an AI assistant that’s a social media influencer.

SLIM (Smart Lander for Investigating Moon)- Japan

Japan recently landed a spacecraft called SLIM (Smart Lander for Investigating Moon) on the lunar surface, becoming the 5th country after the Soviet Union, the US, China and India to achieve a soft landing on the moon. About SLIM SLIM was launched by the Japan Aerospace Exploration Agency (JAXA) in September 2023 aboard the H-IIA rocket from the Tanegashima spaceport. It aims to de

Aditya-L1

Context: With the Aditya-L1 spacecraft expected to reach the Lagrangian Point (L1) on Saturday, the Indian Space Research Organisation (ISRO) will attempt a crucial manoeuvre to bind the spacecraft to an orbit around L1. About the mission: - Aditya-L1 marks India's inaugural space-based observatory-class solar mission designed to scrutinize the Sun from a considerable distance of 1.5 mil

SpaceX’s Falcon-9 to launch India’s GSAT-20; satellite to spread broadband coverage

Context: NewSpace India Ltd. (NSIL), the commercial arm of the Indian Space Research Organisation, will launch GSAT-20 (renamed GSAT-N2), on board SpaceX’s Falcon-9 rocket during the second quarter of 2024. About GSAT-20 Satellite: Features: GSAT-20 is a high-throughput Ka-band satellite equipped with 32 beams, providing comprehensive coverage across India, including remote regio

How AI is changing what sovereignty means

Context: Amidst competitive global politicking, as the world struggles to contain the toxic legacies of 2023 — cruel regional wars, civic conflicts and undeniable stories of anthropogenic harms — technocrats, ecocrats, and bureaucrats across the world continue to device and launch quiet initiatives portending a better and larger future for human rights. Relationship between AI and s

Peregrine & Vulcan

The Peregrine lander was built by Pittsburgh-based space robotics firm Astrobotic and aimed to become the first lunar lander constructed by a private company. This is also the first mission to fly under NASA’s Commercial Lunar Payload Services (CLPS) initiative, where NASA pays private companies to send scientific equipment to the moon. Vulcan Centaur is a two-stage-to-orbit, heavy

National Essential Diagnostics List

The Indian Council of Medical Research (ICMR) has begun the process of revising the current National Essential Diagnostics List (NEDL) and invited relevant stakeholders to offer suggestions on adding or deleting diagnostic tests to the current list by the end of February. National Essential Diagnostics List The NEDL lists the essential and most basic tests that should be available at va

Drug war: On use of antibiotics and antimicrobial resistance

Context: Antimicrobial resistance is a health issue that will negate advances in medicine News: The 'First Multicentric Point Prevalence Survey of Antibiotic Use at 20 NAC-NET Sites India 2021-22,' conducted by the National Centre for Disease Control under the Health Ministry, has revealed alarming statistics. More than 70% of patients in tertiary-care hospitals across 15 Sta

Anti-Microbial Resistance Cause and Solution

Recently the National Centre for Disease Control (NCDC) in a study found that over half of the nearly 10,000 hospital patients surveyed were given antibiotics to prevent, rather than treat, infection. What is Antimicrobial Resistance (AMR)? Antimicrobials - including antibiotics, antivirals, antifungals and antiparasitic - are medicines used to prevent and treat infections in humans, ani

Gut Microbiota and Human Health

Scientists are finding that the gut microbiota may be linked to heart health, some cancers, and even the colour of urine. Gut Microbiota The human gut microbiota refers to the trillions of microbes, such as bacteria, viruses, fungi, and parasites, that live in the human gut. Previously, people referred to the gut microbiota as the microflora of the gut. The gut microbiome i

A new high: On the Aditya-L1 mission and ISRO outreach

Context: On January 6 Aditya-L1 reached its destination, around the L1 Lagrange point, from where it will have an unfettered view of the sun for its expected lifetime of five years. Overview of ISRO: The Indian Space Research Organisation (ISRO) is the space agency of the Government of India, established in 1969, with headquarters in Bengaluru, Karnataka. It is recognized for its cost-e

Thirty Meter Telescope (TMT)

Recently, an official delegation from the Department of Science and Technology visited Mauna Kea to discuss “challenges” to the Thirty Meter Telescope (TMT) project. Thirty Meter Telescope (TMT) It has been conceived as a 30-metre diameter primary-mirror optical and infrared telescope that will enable observations into deep space. It is proposed as a joint

Hot Jupiters

Hot Jupiters are a class of exoplanets that have features similar to Jupiter, but are much closer to their host star & its upper atmosphere is hotter than 1,800 degrees Celcius. The harsh ultraviolet radiation from its star is heating the planet’s upper atmosphere, which in turn causes magnesium and iron gas to escape into space. The star’s powerful gr

Cervical Cancer Vaccine

Indian government is set to roll out a human papillomavirus (HPV) vaccination campaign for girls in the 9-14 years age group. Cervavac is an indigenously developed quadrivalent vaccine by the Serum Institute of India (SII) in Pune, is already available commercially. Immunisation drive – It will be conducted through schools and existing vaccination points, pl

Radiocarbon dating

Context: The technology allowed scholars a clearer and measurable view of the past, clarifying the history of human migration, the rise and fall of civilisations, and undulations of the earth’s climate About: Radiocarbon dating, also known as carbon-14 dating, is a scientific method employed to precisely ascertain the age of organic materials, with its accuracy extending to around 6

Square Kilometre Array (SKA) Observatory

India had decided to formally join the Square Kilometre Array (SKA) project, an international scientific collaboration working to build the world’s largest radio telescope. What is SKA? SKA – It will be the world's biggest and most advanced radio telescope ever constructed. It will not be a single large telescope, but a collection of thousands of dis

TM Module-2 in ICD-11

Recently ICD-11 was launched with the inclusion of Traditional Medicine Module 2. ICD-11 – International Classification of Diseases 11th Revision, the global standard for diagnostic health information. Launched by – World Health Organisation (WHO). Prepared by – WHO in collaboration with Ministry of AYUSH. Aim - To modernize

ISRO launches XPoSat

Context: The Indian Space Research Organisation (ISRO) successfully placed its inaugural X-ray Polarimeter Satellite (XPoSat) into a meticulous circular orbit at an altitude of 650 km following a 21-minute flight on January 1. XPoSat represents the globe's second satellite mission exclusively focused on conducting X-ray polarimetry measurements. About  XPoSat: XPoSat, India's

Zosurabalpin

Researchers have identified a new class of antibiotics named Zosurabalpin with the potential to tackle a drug-resistant bacterium, Acinetobacter baumannii recently. It inhibits the transport of lipopolysaccharide (LPS) molecules. Zosurabalpin was found to be effective against CRAB (carbapenem-resistant Acinetobacter baumannii)-induced pneumonia and sepsis in mice

Halo orbit

Aditya-L1 spacecraft was successfully placed in halo orbit around the Lagrangian point (L1).A halo orbit is a periodic, 3-dimensional orbit that occurs near one of the L1, L2, or L3 Lagrange points. These points are locations in space where the gravitational pull from two celestial bodies is equal. It is called a halo orbit because the tracked orbit looks like a halo

SMART 2.0

Context: The Central Council for Research in Ayurvedic Sciences (CCRAS) along with National Commission for Indian System of Medicine (NCISM) has launched 'SMART 2.0' (Scope for Mainstreaming Ayurveda Research among Teaching professionals) program to promote robust clinical studies in priority areas of Ayurveda with Ayurveda academic institutions/hospitals across the country throu

The global nuclear order is under strain

Context: The current nuclear order has evolved over time, with nine states possessing nuclear weapons: the United States, Russia, France, the United Kingdom, China, India, Pakistan, Israel, and North Korea Background: The global nuclear order is the process by which nuclear weapons affect the world order, dominated by powerful states, mostly from the Global North, with excessive  influence

Starlink

Starlink is a satellite internet network operated by SpaceX, an American aerospace company. It provides coverage to over 70 countries and aims to provide high-speed internet coverage to every part of the world. It also aims to provide global mobile phone service after 2023.

A look back at AI in 2023: The dangers and the hope

CONTEXT: In 2023, the impact of artificial intelligence (AI) on social and economic relations was significant, attributed to the success of large language models (LLMs), such as ChatGPT, in solving complex tasks. Concerns about the dangers of LLMs and publicly deployed AI systems started to be voiced by both industry and state actors, highlighting potential perils that were previously ignored by t

Cosmic Distances

Context: While no human probe has ventured far beyond the boundaries of the Solar System, we possess the capability to measure distances spanning billions of light-years. About: The expanse of space beyond Earth is immensely large, leading to the impracticality of using everyday units of measure. Distances between planets and, more notably, between stars become staggering when expressed

Scope for Mainstreaming Ayurveda Research among Teaching professionals (‘SMART 2.0’)

The Central Council for Research in Ayurvedic Sciences (CCRAS) along with National Commission for Indian System of Medicine (NCISM) has launched 'SMART 2.0' recently. The program aims to promote robust clinical studies in priority areas of Ayurveda with Ayurveda academic institutions/hospitals across the country through mutual collaboration.

Status of persons with disabilities

Context: There needs to be a focus on solutions that enhance the activities of daily life and the quality of life for the disabled News: The United Nations has emphasized the need for "transformative solutions" that promote inclusive development and leave no one behind, refocusing attention on disability-reducing innovations. The field of "neuropsychiatry," situated

Mushroom derived bioactive compounds

Context: Natural anti-infective, antiviral, anti-inflammatory, and antithrombotic products derived from a wide range of easily SOURCEd mushrooms and their bioactive molecules have the potential to combat covid, according to a new paper. News: Bioactive Ingredients and Immune System Boost: The COVID-19 pandemic prompted increased research on bioactive compounds to enhance the immune system

Noma

Context: The World Health Organization (WHO) on December 15, 2023 added one of the world’s most underrecognised health challenges, noma, to its official list of neglected tropical diseases (NTD). Context: The World Health Organization (WHO) on December 15, 2023 added one of the world’s most underrecognised health challenges, noma, to its official list of neglected tropical diseases

Japan’s SLIM ‘moon sniper’ reaches lunar orbit ahead of landmark landing

CONTEXT: Japan will attempt to become just the fifth country in the world to soft-land a spacecraft on the Moon. The Japan Aerospace Exploration Agency (JAXA) announced the successful insertion of its "Smart Lander for Investigating Moon" (SLIM) into lunar orbit at 1:21 PM IST. SLIM's elliptical lunar orbit connects the Moon's south and north poles with a period of about

New Android malware can steal your password by disabling fingerprint and face unlock

CONTEXT: Dubbed 'Chameleon Trojan', the malware uses the 'Accessibility service' on Android devices to disable fingerprint and face unlock and even tracks the user's app usage habits so it can run when the device is not in use. A new version of the 'Chameleon Trojan' malware has been identified by security researchers. The malware is capable of disabling biometr

Ketamine

Context: Ketamine drug was reported to be involved in actor Matthew Perry’s death recently.In recent years, ketamine has been a subject of widespread debate due to its growing use for treating depression and other serious mental health issues. About ketamine: Ketamine, classified as an anaesthetic and hallucinogen by the US Drug Enforcement Administration, is derived from Phenc

NUCLEAR BRIEF CASE

1. The Russian President Vladimir Putin’s recent visit to China was witnessed by his officers carrying the “nuclear briefcase”. The ‘nuclear briefcase’, also known as the ‘Cheget’ is named after a mountain in Russia. It forms a part of a larger system in place for authorising the launch of nuclear strikes. It’s part of a secured communicatio

MARSQUAKE-MARS MISSIONS

Why in the News? Just like on Earth, the surface of Mars sometimes vigorously shakes and unsurprisingly, that is called a marsquake and the largest ever such marsquake was recorded in history happened in 2022. Reason behind the Marsquake: The quake had a magnitude of 4.7 and had seismic signal similar to previous quakes that were caused by meteoroid impacts. However, the po

HEPATITIS C

HEPATITIS C     Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver, a type of viral hepatitis. HCV is spread primarily by Blood-to-blood contact associated with injection drug use Poorly sterilized medical equipment Needlestick injuries in healthcare Tran

ImmunoACT

Why in News? IIT Bombay-incubated Immunoadoptive Cell Therapy (ImmunoACT) has received Central Drugs Standard Control Organisation’s (CDSCO) marketing authorisation approval. ImmunoACT shall be the ‘first’ humanised CD19-targeted Chimeric Antigen Receptor T cell (CAR-T cell) therapy product for relapsed/refractory B-cell lymphomas and leukaemia (blood cancer) in India.

Role of structural inequalities in the incidence of hypertension

    Why in the News? September 29 was observed as the World Heart Day to raise awareness about prevention, detection and treatment of cardiovascular diseases (CVD) and promote heart-healthy lifestyles.   Prevalence of Hypertension in India: National Family Health Survey-5 (2019–2021) revealed that 18.3% of the country’s population ha

INDIA NEEDS TO GO NUCLEAR

INDIA NEEDS TO GO NUCLEAR India’s growing energy needs: India has been registering rapid economic growth and is expected to surpass Germany and Japan to become the third largest economy by the end of this decade. The economic growth triggers demand for energy, which is reflected in India’s primary energy consumption being the third-highest globally, and most of which is base

THE COST OF CHEAP DRUGS

THE COST OF CHEAP DRUGS     Why in the News? Lack of information about effects of unbranded generic medicines hampers patients’ freedom of choice. Generic Medicines: As per FDA, “A generic drug is a medication created to be the same as an already marketed brand-name drug in dosage form, safety, strength, route of administration, quality, performan

Need for an evidence-based traditional medicine

Need for an evidence-based traditional medicine     Why in the News? A plea has been filed by a manufacturer of indigenous drugs against a medical practitioner alleging that his social media thread affected their business. Modern medicine It became science-based in the 19th century, where advances in technology was utilised to study the functioning of the hum

Tele Manas Seva

Tele Manas Seva     Tele Mental Health Assistance and Networking Across States (Tele MANAS) was introduced in the Union Budget 2022. The Tele MANAS entrusted the Ministry of Health and Family Welfare (MoHFW) to guide its overall implementation.  Ranking from first to third, in the larger States category, Tamil Nadu, Maharashtra, and Uttar Pradesh were aw

New tools to fathom the world of electrons

New tools to fathom the world of electrons Why in the News? Recently Pierre Agostini, Ferenc Krausz and Anne L’Huillier have been awarded Nobel Prize in physics, 2023 for their contribution to making it possible to watch electrons move using experimental methods that generate attosecond pulses of light. What is an attosecond? An attosecond is

LIDAR

LIDAR     LIDAR stands for “light detection and ranging” or “laser imaging, detection, and ranging”. It is a method for determining ranges by targeting a surface with a laser and measuring the time for the reflected light to return to the receiver (time of flight). LIDAR scanning or 3D laser scanning involves s

R21 Malaria vaccine

R21 Malaria vaccine     The R21/Matrix-M™ malaria vaccine developed by the University of Oxford and the Serum Institute of India has been recommended for use by the World Health Organization (WHO). The vaccine was developed by leveraging Novavax’s adjuvant technology. The vaccine has met the requirements of safety, quality and effectiveness standards.

India- the Diabetic capital of the world

India- the Diabetic capital of the world     Why in the News? A recent study conducted by the Madras Diabetes Research Foundation in collaboration with the Indian Council of Medical Research and the Union Health Ministry has revealed that 11.4% of India’s population or 10.13 crore people are living with diabetes. 15.3% of the population or an additional 13

Elder Mental healthcare

Elder Mental healthcare     Why in the News? The World Elders Day (1st) and Mental Health Day (10th) has been observed in the month of October, which is significant given the increasingly greying population of India. Increasing old-age population: In the history of humanity, there ar

BlueWalker 3 satellite

BlueWalker 3 satellite     It is a prototype satellite, part of a satellite constellation planned by its owner AST SpaceMobile. The satellite is intended to deliver mobile or broadband services anywhere in the world. BlueWalker 3 was observed as one of the brightest objects in the night sky, outshining all but the brightest stars. However, concerns are raised ar

The trouble with a Nobel for mRNA COVID vaccines

The trouble with a Nobel for mRNA COVID vaccines   Why in the News? The Nobel Prize for Physiology or Medicine, 2023 was given to Katalin Karikó and Drew Weissman for developing the mRNA vaccine technology. The mRNA technology developed by the awardees: messenger RNA (mRNA) is a template used for protein production when genetic information encoded in DNA is tr

Cholera cases

Cholera cases   Cholera is a water-borne disease affecting the small intestine of a person, which can be diagnosed by a stool test or a rapid dipstick test. It is caused by two strains of the bacteria Vibrio cholerae called O1 and O139. While O1 is responsible for almost all outbreaks, outbreaks of O139 have been rare and none recorded outside Asia so far.&

Lagrange Points

Lagrange Points   They are points in space between celestial bodies where a spacecraft stays more or less stationary. Lagrange points are found along the plane of two objects in orbit around their common centre of gravity, where their gravitational forces cancel each other, so that a third body of negligible mass w

R21 Malaria vaccine

R21 Malaria vaccine   The R21/Matrix-M™ malaria vaccine developed by the University of Oxford and the Serum Institute of India has been recommended for use by the World Health Organization (WHO). The vaccine was developed by leveraging Novavax’s adjuvant technology. The vaccine has met the requirements of safety, quality and effectiveness standards. Malaria:

Bacteria Wolbachia

Bacteria Wolbachia   It is a genus of intracellular bacteria that infects mainly arthropod species, including a high proportion of insects, and also some nematodes. It is the most common parasitic microbes, and is possibly the most common reproductive parasite, with as many as 25 to 70% of all insect species are

NASA’s asteroid-hunting spacecraft OSIRIS-Rex

NASA’s asteroid-hunting spacecraft OSIRIS-Rex   Why in the News? Recently, NASA’s asteroid-hunting spacecraft OSIRIS-REx (Origins-Spectral Interpretation-Resource Identification-Security-Regolith Explorer) collected samples from asteroid 101955 Bennu and landed in the Utah desert.  What was OSIRIS-REx’s mission? The OSIRIS-REx spacecr

Tuberculosis (TB)

Tuberculosis (TB)   Why in the News? Recent studies have indicated that nutritional deficiency has led to an increase in TB cases in India, which has been compounded by drug shortages recently. Shortage of Rifampicin, a medicine used for treating drug sensitive TB was not available in many parts of India

TrueNat Test

TrueNat Test   TrueNat is a is a chip-based, battery-operated RT-PCR kit for point-of-care and rapid molecular test for diagnosis of infectious diseases. RT-PCR (Reverse Transcriptase- Polymerase Chain Reaction) employs reverse transcription process that converts RNA into DNA molecule before the gene can be captured in the test. It was used as a screening test during COVI

India’s kidney transplant deficit

India’s kidney transplant deficit Why in the News? India’s organ shortage has increased alarmingly, for which government’s recent reforms (February 2023) allow more flexibility in age and domicile requirements while registering to obtain an organ. Kidney transplantation in India: There is a high prevalence of chronic kidney disease (CKD) in India, affecting about 1

Monoclonal Antibodies

Monoclonal Antibodies     Monoclonal antibodies are laboratory-made proteins that mimic the behaviour of antibodies produced by the immune system to protect against diseases and foreign substances It attaches itself to an antigen such as Glycoproteins (a foreign substance, usually a disease-causing molecule) and helps the immune system eliminate it from the body.

Echolocation

Echolocation     A technique in which animals or devices emits sound waves, and listens for their reflections by objects in their surroundings. The sound waves emitted will be in the nature of high-frequency sound pulses, often beyond the range of human hearing.  Bats due to their poor eyesight uses this ability to hunt and navigate in the dark, while do

Omega Fatty acids

Omega Fatty acids Polyunsaturated fatty acids (PUFA) or called as “essential” fatty acids are Omega-3 and Omega-6. They play in controlling two key body processes: Blood clotting Inflammation. It prepares the body to fight back infection and injury but for prolonged periods can also cause severe damage and chronic illnesses. Both have to be in right ratio to

ICMR study on long COVID

ICMR study on long COVID     Why in the News? A recent study was conducted by the Indian Council of Medical Research (ICMR) on the post Covid-19 conditions and its report has been recently published. The WHO estimates that 10 to 20 per cent of Covid patients develop prolonged symptoms. Key findings of the Study: Nearly 6.5% people hospitalised

One Health can help India respond better to health crises

How One Health can help India respond better to health crises   Why in the News? India has been taking significant strides for the adoption of a ‘National One Health Mission’ to be led by the Office of the Principal Scientific Advisor. The concept of ‘One Health Strategy’: It is a holistic approach recognises the problems among the inte

Artificial Intelligence (AI)

Why in the news? The number of organisations adopting AI technology in India has gone up by 2.5 times with widespread applications in education, health, finance, mobility and e-commerce among others.   What is AI? AI is the intelligence of a machine to work based on human cognitive skills that has the ability to reason, discover meaning, generalize or learn from past experience, d

Lymphatic Filariasis

Lymphatic Filariasis India is committed to eliminate Lymphatic Filariasis by the year 2027, three years ahead of the global target of 2030. Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease.     It is caused by mosquitoes when they transmit filarial parasites (classified as nematodes) to humans causing infection. Three

Climate Events and an umbrella for Urban Health

Climate Events and an umbrella for Urban Health The Monsoon season in India has led to large scale devastation with events of Cyclonic storm Biparjoy, floods in the state of Assam and heavy rain led damages in parts of North India. But the climate events also pose a challenge of common water and Vector-borne diseases especially in the Urban centres. Disease Vulnerability in the urban areas:

Learning from the CHIPS Act of the US

Learning from the CHIPS Act of the US Why in the news? The United States’s Creating Helpful Incentives to Produce Semiconductors and Science (CHIPS) Act, 2022 which aims to strengthen its semiconductor industry, has completed one year as a law. What are the Provisions of the law and what lessons can India learn from it?     Provisions o

Tuberculosis

Tuberculosis Why in the News? A large trial involving ~2800 people conducted in India has revealed that nutritional support plays a key role in cutting down tuberculosis (TB) disease rate and mortality reduction in TB infected patients. TB and Nutritional deficit: Severe undernutrition is one of the contributing causes of deaths in TB patients. Undernutrition as a risk factor acc

Medicines Patent Pool Agreement for Leukaemia

Three firms with headquarters in India have inked sub-licence agreements with the Medicines Patent Pool (MPP), a United Nations-backed organisation, to make some cancer medications more affordable and available to patients. These agreements permit the manufacturing of generic versions of the cancer medication Nilotinib, which is primarily used to treat Chronic Myeloid Leukaemia (CML)

National Guidelines for Organ Transplantation

The National Organ and Tissue Transplant Organization's guidelines contained a stipulation that only allowed patients under the age of 65 to register for transplants. This rule has been abolished by the Union Health Ministry. The Transplantation of Human Organs Act, 1994 in India sets up a number of rules regarding the removal and preservation of human organs. Additionally, it controls th

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ACQ IAS
ACQ IAS