Daily News Analysis

Hydroxyurea

stylish_lining

The Indian Council of Medical Research (ICMR) invited Expressions of Interest (EoI) from various organisations for the “joint development and commercialisation” of low dose or paediatric oral formulation of hydroxyurea to treat sickle cell disease in India.

About Hydroxyurea (taken orally in the form of capsules or tablets)

• It's a medication used to treat certain types of cancer, such as chronic myelocytic leukemia (CML) and some head and neck cancers, as well as to reduce the frequency of painful crises in people with sickle cell anemia.

• It works by slowing the growth of rapidly dividing cells, including cancer cells and bone marrow cells that produce abnormal red blood cells in sickle cell disease.

Hydroxyurea inhibits the enzyme ribonucleotide reductase, which is crucial for DNA synthesis. It is used to decrease the high platelet count, reducing the risk of thrombosis.

Polycythemia Vera condition involves the overproduction of red blood cells. Hydroxyurea helps reduce the red blood cell count, lowering the risk of blood clots & other complications.

Common side effects: nausea, vomiting, diarrhea, loss of appetite, mouth sores, hair loss, and skin rash, decreasing levels of red blood cells, white blood cells, and platelets in the blood.

Women in Armed Forces

The first-ever batch of 17 female cadets graduated from the National Defence Academy (NDA), marking a historic step toward greater gender inclusion in India's armed forces. Significance of
Share It

Global Tobacco Epidemic 2025

The World Health Organization (WHO) has released its tenth report on the Global Tobacco Epidemic 2025, highlighting the progress made in reducing tobacco use globally and pointing out areas that s
Share It

Special Rupee Vostro Accounts (SRVAs)

SRVAs are accounts opened by foreign entities with Indian banks that allow international trade transactions to be settled in Indian Rupees (INR) rather than traditional global currencies like the
Share It

WTO in Shaping Global Trade Dynamics

The World Trade Organization (WTO) plays a pivotal role in shaping the global trade environment by providing a multilateral platform for negotiating and enforcing trade agreements, ensuring that i
Share It

Quality Council of India (QCI)

Recently, the National Accreditation Board for Testing and Calibration Laboratories (NABL), a constituent body of the Quality Council of India (QCI), launched its new Medical Application Portal.
Share It

Cultural Appropriation

Cultural appropriation refers to the adoption of elements from one culture by members of another, often in ways that exploit, disrespect, or commodify the original culture. This becomes particular
Share It

Cultural Capital and Its Significance in India

Cultural capital refers to the non-economic assets such as education, knowledge, and cultural practices that contribute to social mobility. It was coined by French sociologist Pierre Bourdieu to e
Share It

QS World University Rankings 2026

India’s higher education system has shown significant improvement in the QS World University Rankings 2026, with a notable increase in the number of Indian universities ranked globally Ab
Share It

India's Semiconductor Market

India’s semiconductor industry is witnessing rapid growth and is expected to continue its upward trajectory, driven by several key trends and emerging opportunities. Market Size and Growth
Share It

Cess

A cess is an additional tax imposed by the Government of India for a specific purpose, as authorized under Article 270 of the Indian Constitution. It is levied on top of existing taxes or duties l
Share It

Newsletter Subscription


ACQ IAS
ACQ IAS